Amost certainly not. Galaxies aren't concrete objects, they're just a collection of objects with a truly vast amount of space in between them. You might try and change all of the largest bdy in that galaxy into energy by using antimatter, but I doubt that would be enough to do anything noticable to the entire galaxy.
The galaxy will explode if its central mass is destablized enough to cause all matter to ossilate between 12 HZ and 40 HZ.
Easily countered by reversing the polarity of the No. 4 shield to cause a Garyon flux, hyper-collapsing the quantum-nano arrays.
The distance between stars in a galaxy is too vast. Two galaxies of a hundred billion stars might pass through each other with disruption but without two stars colliding. Parts of the 'chain' would be akin to a firecacker going off in the UK and having to ignite the next one...in California.
if you could somehow manipulate to fabric of the universe cancelling out effects like gravity and manipulate other natural laws on a galaxy scale... sure
Well Galaxies more likely come FROM explosions(big bang), their "deaths" probably look like huge black holes. http://en.wikipedia.org/wiki/Crab_Nebula is the nastiest thing in recent human memory and it is not goingto take out the milky way.
http://www.nasa.gov/home/hqnews/2006/dec/HQ_06373_Hybrid_Burst.html Dwayne Brown Headquarters, Washington 202-358-1726 Susan Hendrix Goddard Space Flight Center, Greenbelt, Md. 301-286-7745 Dec. 20, 2006 RELEASE: 06-373 NASA Satellite Discovers New Kind of Black Hole Explosion GREENBELT, Md. - Scientists using NASA data are studying a newly recognized type of cosmic explosion called a hybrid gamma-ray burst. As with other gamma-ray bursts, this hybrid blast is likely signaling the birth of a new black hole. It is unclear, however, what kind of object or objects exploded or merged to create the new black hole. The hybrid burst exhibits properties of the two known classes of gamma-ray bursts yet possesses features that remain unexplained.
