Reprogrammed adult stem cells identical to embryonic stem cells confirmed

Discussion in 'Biology & Genetics' started by Plazma Inferno!, Jun 14, 2016.

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    Researchers from the Vavilov Institute of General Genetics, Research Institute of Physical Chemical Medicine and Moscow Institute of Physics and Technology (MIPT) have concluded that reprogramming does not create differences between reprogrammed and embryonic stem cells.
    Scientists distinguish several types of stem cells. Stem cells that can potentially produce any cell in the body are called pluripotent stem cells. There are no pluripotent stem cells in an adult body; they are found naturally in early embryos.
    There are two ways to get pluripotent stem cells. The first is to extract them from the excess embryos produced during the in vitro fertilization procedure. But this practice is still controversial technically and ethically because it does destroy an embryo which could have been implanted. This is why researchers came up with the second way to get pluripotent stem cells – reprogramming adult cells.
    The process of "turning on" genes that are active in a stem cell and "turning off" genes that are responsible for cell specialization is called reprogramming. This technology was pioneered by Shinya Yamanaka, who showed that the introduction of four specific proteins that are essential during early embryonic development could be used to convert adult cells into pluripotent cells. He was awarded the 2012 Nobel Prize along with Sir John Gurdon "for the discovery that mature cells can be reprogrammed to become pluripotent."

    http://phys.org/news/2016-06-scientists-reprogrammed-adult-stem-cells.html
     

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