The Emergence of Life:

Discussion in 'Biology & Genetics' started by paddoboy, Nov 10, 2017.

  1. paddoboy Valued Senior Member

    New study sheds light on how earliest forms of life evolved on Earth
    November 10, 2017

    A new study led by ANU has shed light on how the earliest forms of life evolved on Earth about four billion years ago.

    In a major advance on previous work, the study found a compound commonly used in hair bleach, hydrogen peroxide, made the eventual emergence of life possible.

    Lead researcher Associate Professor Rowena Ball from ANU said hydrogen peroxide was the vital ingredient in rock pores around underwater heat vents that set in train a sequence of chemical reactions that led to the first forms of life.

    "The origin of life is one of the hardest problems in all of science, but it is also one of the most important," said Dr Ball from the Mathematical Sciences Institute and Research School of Chemistry at ANU.

    The research team made a model using hydrogen peroxide and porous rock that simulated the dynamic, messy environment that hosted the origin of life.

    Read more at:

    the paper:

    Toy trains, loaded dice and the origin of life: dimerization on mineral surfaces under periodic drive with Gaussian inputs:

    In a major extension of previous work, we model the putative hydrothermal rock pore setting for the origin of life on Earth as a series of coupled continuous flow units (the toy train). Perfusing through this train are reactants that set up thermochemical and pH oscillations, and an activated nucleotide that produces monomer and dimer monophosphates. The dynamical equations that model this system are thermally self-consistent. In an innovative step that breaks some new ground, we build stochasticity of the inputs into the model. The computational results infer various constraints and conditions on, and insights into, chemical evolution and the origin of life and its physical setting: long, interconnected porous structures with longitudinal non-uniformity would have been favourable, and the ubiquitous pH dependences of biology may have been established in the prebiotic era. We demonstrate the important role of Gaussian fluctuations of the inputs in driving polymerization, evolution and diversification. In particular, we find that the probability distribution of the resulting output fluctuations is left-skewed and right-weighted (the loaded dice), which could favour chemical evolution towards a living RNA world. We tentatively name this distribution ‘Goldilocks’. These results also vindicate the general approach of constructing and running a simple model to learn important new information about a complex system.
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