Aging

Asexperia

Asexperia

Valued Senior Member
Why do we age?

Is it due, perhaps, to the oxygen of the mitochondria of the cells?
Or is it due to other causes?
 
A good video to dig into the problem.
I also watched an interesting TED talk once, which i cannot find right now, claiming that iron oxidation played a big role
 
I been rode hard and put away wet. I'm surprised I'm even close to 69 years old. The damage is as the doctors predicted back in the '70s. But lawsy me, I had fun.
 
Asexperia said:
Why do we age?

Is it due, perhaps, to the oxygen of the mitochondria of the cells?
Or is it due to other causes?
Click to expand...

Our cells are genetically programmed to die, a property known as senescence. They have a set number of times that they can divide, after which they stop dividing and die. This death can be deliberate (ie. the cells commit suicide via a process called apoptosis), or it can simply be by accumulation of environmental damage that can be quick or prolonged, depending on the cell type and its function.

The only cells that are not programmed to die are stem cells. Stem cells are the engines that drive tissue regeneration by cell division; they replace the cells that die through senescence. However, over time stem cells accumulate genetic damage and gradually lose their ability to regenerate tissues and organs. Thus, your body gradually deteriorates over your lifetime.
 
Asexperia said:
Why do we age?
Click to expand...

There are lots of theories, but nobody really knows.

I find it interesting that what we think of as biological organisms do age, life itself appears to be immortal. When we have children, those children become new organisms and seem to start the clock over and don't inherit their parents' age.

There's a continuous chain of life leading back from each of us back to the first cells on Earth. No gaps. Life seems to need to reproduce for some unknown reason, but as long as it does that, there doesn't seem to be any limit on how long the chain of life can last. It's seemingly been here on Earth for upwards of 3 1/2 billion years already.
 
Asexperia said:
Why do we age?

Is it due, perhaps, to the oxygen of the mitochondria of the cells?
Or is it due to other causes?
Click to expand...

well, whilst all the cells in our body work the way they have to to keep us young, we stay young.
so they must stop working that way.

genes determine almost everything about the cell, so the way I see it,

functional genes=functional cells=functional body

these functional genes can be achieved by ingestion of NMN, which makes sure they are undamaged and expressed properly,
in combination with TA-65 which makes sure that the genes stay this way by protecting them with telomeres.
 
DaveC426913 said:
All things age.

Entropy and thermodynamics cannot be outrun.

Why would we not age?
Click to expand...

it doesn't matter if the body is subject to entropy, per se,
because the whole body is replaced every 10 years or so anyway.
my aim is to make this process of renewal indefinite, and the renewed body a functional one.
 
just me said:
it doesn't matter if the body is subject to entropy, per se,
because the whole body is replaced every 10 years or so anyway.
Click to expand...
That renewal isn't magic or automatic. The machinery that replaces parts of us is not perfect - and it too ages.
 
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