What is the cause to vomit

Discussion in 'Health & Fitness' started by timojin, Feb 6, 2017.

  1. timojin Valued Senior Member

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    Why mary Jane (marijuana ) reduces desire to vomit ?
     
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  3. origin Trump is the best argument against a democracy. Valued Senior Member

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    I am not sure. I will run a series of experiments to find out. I just hope I can remember the results...

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  5. DaveC426913 Valued Senior Member

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    Can you cite a reference that shows it does?

    A quick Google suggests that marijuana often induces vomiting (hyperemesis).
     
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  7. timojin Valued Senior Member

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    If I would know I would not put a question mark at the end of the post
    I am not going to cite anything , to my understanding is commonly used by patient getting chemotherapy,
     
  8. timojin Valued Senior Member

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    Thanks for being funny .
     
  9. DaveC426913 Valued Senior Member

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  10. Fraggle Rocker Staff Member

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    25 years ago the son of two friends of mine had cancer. He was put on chemotherapy, but as you've noted, it is an appetite reducer, so the patient might starve to death as the cancer goes into remission. My friends planted a marijuana garden in their back yard--with the unspoken approval of their neighbors and even the local cops--and he began eating and gaining weight. I haven't seen these folks in years, but the last I heard, ten years later,their son was alive and healthy with no signs of relapse.
    That's preposterous! Americans have smoked tons of marijuana (or drank it in tea, or cooking it into pastry) since the early 1970s. There are a lot of bad things that can happen, but absolutely NO ONE has ever reported nausea as a side effect. The problem is, in fact, just the opposite: "the munchies."

    Sure, somebody somewhere has a weird metabolism, or some kind of illness, that causes nausea, but none of the hundreds of pot-heads I've known over the past 45 years has ever met this poor fellow. Meanwhile, chemists are frantically attempting to breed a new strain of marijuana plants that will increase appetite without the intoxicating effect.
     
  11. DaveC426913 Valued Senior Member

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    I did not think it was a thing either, until I Googled 'marijuana and vomiting', expecting links about relief from vomiting. Instead, there is quite a lot of literature about a correlation. It's called
    Cannabinoid Hyperemesis Syndrome.
     
  12. timojin Valued Senior Member

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    Now that you learned something , let's back to the question. What component are in MJ. that control vomiting , since this is a science forum.
     
  13. DaveC426913 Valued Senior Member

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    Well, simply: I do not know. I could find out and report back here, but I'd be doing the same thing you would: Googling.
     
  14. Beaconator Registered Senior Member

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    Does that mean it gets to the plateau quickest?
     
  15. Beaconator Registered Senior Member

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    So they added mold to it...
     
  16. Stoniphi obscurely fossiliferous Valued Senior Member

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    Cannabis is used to repress nausea of many kinds and types. It engages the CB1 and CB2 receptors in your central nervous system.

    Migraine sufferers appear to develop a resonance effect in the paraquaductal grey area of their brain when they experience a particular type of head/neck pain. As the nerve pain signals bounce back and forth within that region the sensation of pain increases and the person then begins to vomit. When they have no stomach contents left to vomit they move into the dry heaves. This cycle can extend over days or weeks, totally debilitating the person. They can become extremely sensitive to light and sound - ANY light and sound.

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    My wife is a migraine sufferer. When she got a headache, she would go through the above cycle and end up in the Lazy Boy recliner with a hot pad on her face, a bucket on the floor next to her and an intolerance for any sounds at all. When I read that cannabis might help her, I procured a small amount and we used that as an intercession as she became nauseous with a migraine. It worked very well, stopped the pukes so she could take some Tylenol and keep them down which stopped the headache. She made me promise to always keep some cannabis on hand for this purpose. My wife does NOT enjoy cannabis or getting high, but she does not like the migraine pukes at all, that is the only time she will use cannabis and then only enough to be effective.

    Later, I had throat surgery and had to take Oxycontin for the pain. Opiates give me intestinal cramps, bad nightmares and sudden nausea attacks. When the pukes started coming on I would hit my Vapor Brothers vaporizer to stop that. It worked very well and almost immediately.

    When I went on 2 & 1/2 years of Luprolide chemotherapy for the prostate cancer I again began having sudden nausea attacks. Those stayed around after the therapy ended too...I haven't had an attack in about 2 months now though, keeping my fingers crossed.

    It is believed that the component in cannabis that specifically stops nausea is cannabidiol, or CBD, which engages CB2 receptors. Thus the 'med strains' that have lots of CBD and very little tetrahydrocannabinol or THC which does get you stoned.

    A decent source for medical applications of cannabis is the National Academy of Science School of Medicine Report to Congress on Marijuana and Medicine. I have a collection of research articles, papers and books on this topic.

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    EDIT: The mold comes along with low grade schwag for free.

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    Also, a novice who 'overdoses' can get the pukes when they freak out....right before they go to hospital for doggy downers.

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  17. timojin Valued Senior Member

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    Do you have to smoke it ,or can be used in dissolved water ?
     
  18. Stoniphi obscurely fossiliferous Valued Senior Member

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    I prefer neither. I do not smoke anything as that is bad for your lungs. I use a Pax 2 or a Volcano vaporizer which heats the cannabis enough to release its active ingredients without burning it. You inhale the vapor it generates. The effects are rapid, but not as strong as if it was smoked. The speed is important if you are trying to stop from puking as that comes on quickly.

    The active ingredients are not water soluble, so you must dissolve those in alcohol if you wish to drink it. The active ingredients also dissolve in oil, so powdered cannabis can be mixed with butter and used in recipes that call for that, like cookies and candy. They call those "Medibles".
     
  19. DaveC426913 Valued Senior Member

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    You can extract the oils and mix it into foods.

    I have a friend with arthritis who makes a butter, and uses it in baking.

    Used this way, it eases pain but doesn't get you high.
     
  20. timojin Valued Senior Member

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    Do you have any idea as to why the person get nauseous. ? When nausea is set in , the person does not have appetite , does not want to smell any food , (I grant you been dizzy can cause nausea ) .
    In other words I am curious what is the mechanism to set in nausea. My healthy dog died , and he little by little was refusing his favorite food like ham. cold cuts and other meat product,I noticed he he smelled the food and become nauseous.
     
  21. DaveC426913 Valued Senior Member

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    Nausea is the body's alert to you to not take in anything more that might harm you.
    It also encourages reverse peristalsis for ejecting what you ahve already eaten.

    It is not a perfect defense. But Early Man did not evolve on fun rides at the circus.
     
  22. timojin Valued Senior Member

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    I like your first two lines,
    The question what part of the body recognise , than to send a signal to the brain which engages to the " CB2 " receptor. To me it could come from some particular organ in the body ?
     
  23. Stoniphi obscurely fossiliferous Valued Senior Member

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    Not necessarily. The paraquaductal grey region is supposed to dampen pain signals, but sometimes in some people is does not do that. A migraine headache, severe shoulder pain, an inner ear balance problem and a bunch of other things can overwhelm that brain area such that the pain resonates in waves of pain signals that wash back and forth through the area like waves of water in a bath tub until the person vomits.

    There are other things that can make you vomit though. Trying to swallow a raw egg or drink something that tastes very bad, eating something that produces too much stomach acid..those will all make you vomit as well. They involve your sense of taste, your sense of smell and your stomach's ability to know when its contents are too acidic to process are all different mechanisms that can lead to nausea.

    I would bet that the pathways those stigmata take into your brain are all different as well.
     

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