If we're really it, isn't there hope that the universe can continue without our help? That would be a joyful day!
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As I said, the chances we are alone are remote.
If we are, as also mentioned our creationists friends will have a field day!
But yeah, the possibility that they are so advanced, say a type 3 or 4 on Kardashev scale, that we are like ants on an anthill to them.....