Any objective explanation of life needs to include the impact of water within the discussion. The subjective explanations of life will always leave out the impact of water in bio-physical chemical discussion. As a simple experiment, let us start with series of beakers, each with life at all the levels. Some have enzymes, others DNA, others cells , others multicellular, etc. If we remove the water, nothing works properly in any of the beakers. Without the water there is no sign of life only inanimate organics.
Next, let us substitute any other solvent known to man, in any go these beakers. We can do a slow exchange beginning with water and extractions so everything stays wet. In the end, nothing works properly and still there are no signs of life even though we have all the organics needed and a new solvent. Any objective person, not bound by subjective traditions, will infer that water is critical to life at all levels and cannot be rationally ignored. It can be subjectively ignored and substituted for with casino math to find jackpots.
The importance of water is multi-fold. The primary impact is connected to the natural potential between organics and water; water and oil. Water is polar and all the organics have non-polar moieties. These opposites tend to separate, from nano-scale to macro levels depending on the chemical.
The result is the water continuum (majority component of life) creates the dominant potential with all the organics needing to align, combine and change in ways that help lower the short and long term potential between the two phases. It is not coincidence that life ended up using hydrogen bonding. This was needed to lower the potential of water since water used hydrogen bonding first. It is not coincidence the DNA came late in the process because DNA is the most hydrated molecule within life. RNA is less hydrated and came before. Evolution was/is directional and based on the organics needing to conform to water. That conforming pays off with all things able to because active in the potential flux.
Another important impact of water is the entropic force, which is a fifth force of nature, that is common to life. Life makes use of semipermeable membranes that restrict the free flow of materials into and out of the cell and other places within the cell. Transport proteins are used to allow specific organic materials to pass through these membranes, at particular spots.
Water is different in that it has free access to move back and forth. The water will spontaneously move in the direction of higher entropy (highest concentration of materials and moieties). This direction of motion, based on entropy, results in more water randomization. Although random on the surface, will nevertheless create a that force connected to osmotic pressure; pressure equals to force/area, that is directional and ordered.
This entropic force is created by random but itself is not random but directional. This is possible in liquid state physics. This unique entropic force has been called the life force, since it is used by life. This force can help push and pull to trigger specific activities. While the continuity of water, throughout the cell, allows the entropic force to be applied in spatial ways for integrated activity and change. This force also assists evolution and goes beyond the subjective of the random models that leave out water as a co-variable with as much impact as the organics.